Team:Montgomery Cougars NJUSA

From 2014hs.igem.org

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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
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{{Montgomery Cougars NJUSA/Layout:Home Page}}
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|[[Image:Montgomery_Cougars_NJUSA_logo.png|200px|right|frame]]
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=Montgomery iGEM=
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
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|[[Image:Montgomery_Cougars_NJUSA_team.png|right|frame|Your team picture]]
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|align="center"|[[Team:Montgomery_Cougars_NJUSA | Team Montgomery_Cougars_NJUSA]]
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<!--- Team Information Link --->
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Motivated by the lack of outlets for students to explore their passions for biological research, students from Montgomery High School created their own iGEM team in the 2013-2014 academic year to gain firsthand experience in synthetic biology. While the beginning of the season presented numerous obstacles, Montgomery iGEM has developed into a successful club with over 30 active members who are all motivated by the endless possibilities that scientific innovation presents.
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Our club stemmed from a desire to provide students with hands-on laboratory experience. While popular clubs in our school such as Robotics and Science Olympiad provide great opportunities for students to explore and learn about new fields of science and engineering, students previously did not have the opportunity to engage in wet laboratory practices. We created this team to provide students with a firsthand look into the strikingly innovative field of synthetic biology and an opportunity to innovate. We strive to further student interest in science and increase students' exposure to fields that they might not have explored otherwise. Our iGEM program is creating the next generation of doctors, biomedical engineers and innovators, a generation with a genuine desire to help make the world a better place.
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!align="center"|[https://igem.org/Team.cgi?year=2013&division=high_school&team_name=Montgomery_Cougars_NJUSA Official Team Profile]
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===Team===
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[[Image:Montgomery Cougars NJUSA team.jpg|700px|center|thumb]]
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[[Team:Montgomery Cougars NJUSA/About|About Our Team]]
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{{Montgomery_Cougars_NJUSA/Layout_End:Home_Page}}
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[[Team:Montgomery Cougars NJUSA/Team Log|Team Log]]
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Montgomery iGEM was created because our school does not currently offer many outlets for students to explore their passions in biological research, including pre-medicinal studies. Many students are under the impression that science is limited to the engineering aspects such as electrical and mechanical building; the goal of our team is to allow students to explore their passion for researching various scientific topics. This program aims to create the next generation of doctors, biomedical engineers and innovators in science. With the introduction of iGEM into the extracurricular community of Montgomery High School, the possibility of achieving these goals is greatly increased.
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===Project===
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== The Role of P. acnes in Acne Vulgaris ==
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The bacteria Propionibacterium acnes is responsible Acne Vulgaris (more commonly acne). Although P.Acnes is no issue in most people, there are certain virulent strains that exacerbate acne inflammation. The bacteria thrives in the presence of lipids, specifically sebum, which is P.Acnes’s primary source of energy and sustenance. An increase of sebum production attracts bacteria into hair follicles, where the bacteria can multiply and colonize, an inflammatory reaction that results in cysts and pustules, which can lead to scars.
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== Project Description ==
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For the 2014 Competition season, Montgomery_Cougars_NJUSA aims to create a better solution for acne reduction. Acne is a problem that affects nearly 80% of American adolescents. Unfortunately, this widespread problem does not have a concrete solution. Proactiv, a leading acne medication company, uses salicylic acid to burn off skin and bacteria alike from the patient’s face. This method is moderately painful and is not always 100% effective. So, to combat this widespread ailment, Montgomery iGEM has decided to take a different approach.
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In an effort to create a better product, we decided to produce an enzyme to break down the sebum on human skin, thereby reducing the bacteria's source of energy and ability to colonize. Because sebum is made of of triglyceride oils, wax, squalene, and metabolites of fat-producing cells, we sought a group of enzymes that would break down these components. To counter each of these components, we have tracked down enzymes such as wax-ester hydrolase, triglyceride lipase, squalene monooxygenase, HMG CoA Reductase and Lipoprotein Lipase. Throughout the next few weeks, we plan to find genes that we can transform bacteria with to include these enzymes. Our final product will include genes that code for many of these enzymes, increasing our chance of reducing nutrients for acne-inducing bacteria.
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== References ==
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===Notebook===
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[[Team:Montgomery_Cougars_NJUSA/Notebook|View our Lab Notebook]]
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===Results/Conclusions===
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What did you achieve over the course of your semester?
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===Safety===
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Safety is a primary goal for our iGEM team. To ensure that everyone working on experiments follow all safety precautions, we developed a number of safety presentations about a number of topics such as personal protective equipment, aseptic technique, and laboratory practice. Finally, we ensured comprehension by administering a safety exam for all R&D members.
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===Attributions===
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Who worked on what?
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===Human Practices===
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What impact does/will your project have on the public? 
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===Fun!===
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What was your favorite team snack?? Have a picture of your team mascot?
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Latest revision as of 22:05, 19 June 2014

Montgomery iGEM

Motivated by the lack of outlets for students to explore their passions for biological research, students from Montgomery High School created their own iGEM team in the 2013-2014 academic year to gain firsthand experience in synthetic biology. While the beginning of the season presented numerous obstacles, Montgomery iGEM has developed into a successful club with over 30 active members who are all motivated by the endless possibilities that scientific innovation presents.

Our club stemmed from a desire to provide students with hands-on laboratory experience. While popular clubs in our school such as Robotics and Science Olympiad provide great opportunities for students to explore and learn about new fields of science and engineering, students previously did not have the opportunity to engage in wet laboratory practices. We created this team to provide students with a firsthand look into the strikingly innovative field of synthetic biology and an opportunity to innovate. We strive to further student interest in science and increase students' exposure to fields that they might not have explored otherwise. Our iGEM program is creating the next generation of doctors, biomedical engineers and innovators, a generation with a genuine desire to help make the world a better place.

Montgomery Cougars NJUSA team.jpg

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