Team:Montgomery Cougars NJUSA/Project/PathogenesisofAcne
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==Pathogenesis of Acne== | ==Pathogenesis of Acne== | ||
- | Acne Vulgaris | + | Acne Vulgaris results due to blocked follicles. Comedogenesis is the obstruction of sebaceous follicles due to greater cohesiveness of the follicular epithelial cells and sebum. In this environment, the bacteria ''Propionibacterium acnes'' proliferates and causes inflammation, and consequently inflammatory papules, pustules, and nodulocystic lesions. Another factor, excessive sebum production is caused by androgenic stimulation of sebaceous glands. |
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+ | =The Role of Sebum= | ||
+ | An increase in sebum is a direct result of increased production of adrenal and gonadal androgens (which occurs during the onset of puberty). | ||
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Revision as of 19:00, 30 May 2014
Pathogenesis of Acne
Acne Vulgaris results due to blocked follicles. Comedogenesis is the obstruction of sebaceous follicles due to greater cohesiveness of the follicular epithelial cells and sebum. In this environment, the bacteria Propionibacterium acnes proliferates and causes inflammation, and consequently inflammatory papules, pustules, and nodulocystic lesions. Another factor, excessive sebum production is caused by androgenic stimulation of sebaceous glands.
The Role of Sebum
An increase in sebum is a direct result of increased production of adrenal and gonadal androgens (which occurs during the onset of puberty).
Our Project
- Project Overview
- Pathogenesis of Acne
- Selecting the Gene
- Registry Parts
- Mathematical Model
- Error Analysis