Team:TP CC-SanDiego/Mentors

From 2014hs.igem.org

(Difference between revisions)
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{{Team:TPHS/Main}}
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{{{Team:TPHS/Main}}
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<h1>Team Members</h1>
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 +
<div id="Carousel">
 +
<div id="LeftArrow" class="Arrow"></div>
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<div id="Person0" class="Person Slide0"></div>
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<div id="Bio0" class="Info">
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<div class="InfoImg"><img src="https://static.igem.org/mediawiki/2013hs/e/e2/GhaYoungPortrait%28s%29.jpg"></div>
 +
<div class="Text">
 +
<h2>Gha Young Lee</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
 +
</div>
 +
</div>
 +
<div id="Bio1" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Michael Margolis</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
 +
</div>
 +
</div>
 +
<div id="Bio2" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Brandon Read</h2>
 +
<h3>Senior at Torrey Pines High School</h3>
 +
<p></p>
 +
 +
</div>
 +
</div>
 +
<div id="Bio3" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Mokhshan Ramachandran</h2>
 +
<h3>Senior at Torrey Pines High School</h3>
 +
<p></p>
 +
 +
</div>
 +
</div>
 +
<div id="Bio4" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Brian Choi</h2>
 +
<h3>Senior at Torrey Pines High School</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio5" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Anisa Malangone</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio6" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Victoria Ouyang</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio7" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Melinda Wang</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio8" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Christina Baek</h2>
 +
<h3>Sophomore at Torrey Pines High School</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio9" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Evan Kallenberg</h2>
 +
<h3>Senior at Torrey Pines High School</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio10" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Ellen Ouyang</h2>
 +
<h3>Sophomore at Canyon Crest Academy</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio11" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Daniel Sands</h2>
 +
<h3>Junior at Canyon Crest Academy</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio12" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Aidan Kahng</h2>
 +
<h3>Sophomore at Torrey Pines High School</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio13" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Zilu Pan</h2>
 +
<h3>Sophomore at Carmel Canyon Academy</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio14" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Nikki Nikkhoy</h2>
 +
<h3>Junior at Torrey Pines High School</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
<div id="Bio15" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Alexander Wen</h2>
 +
<h3>Freshman at Torrey Pines High School</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio16" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Amanda Matheson</h2>
 +
<h3>Sophomore at Carmel Canyon Academy</h3>
 +
<p></p>
 +
</div>
 +
</div>
 +
<div id="Bio17" class="Info">
 +
<div class="InfoImg"><img src=""></div>
 +
<div class="Text">
 +
<h2>Julia Wisnia</h2>
 +
<h3>Freshman at Carmel Canyon Academy</h3>
 +
<p></p>
 +
<h3></h3>
 +
</div>
 +
</div>
 +
 +
</div>
 +
</div>
 +
</body>
 +
</html>

Revision as of 23:48, 9 March 2014

{ iGEM San Diego

STATISTICS
Statistics that are quite relevant to the nature of this experiment

Toxicity of aflatoxin is 10 times that of hydrocyanic acid and 68 times of arsenic.

This disease is the third-leading cause of cancer death globally according to WHO (2008), with about 550,000–600,000 new cases each year.

This disease is the third-leading cause of cancer death globally according to WHO (2008), with about 550,000–600,000 new cases each year
ENGINEERING
E. Coli Capable of Extracelluar Secretion of Mycotoxin Detoxifying Enzymes
Microfungi that produce harmful mycotoxins flourish on improperly-stored nuts, grains, meat, and dairy. They especially thrive in developing countries, where the lack of advanced food storage and mycotoxin exposure causes 40% of the diseases. To lessen the problem, our team engineered E. coli strains using synthetic biology tools to produce chimeric mycotoxin-degrading fungal enzymes, Aflatoxin-Detoxifizyme (ADTZ) and Zearalenone Hydrolase (ZHD101), which are designed to be secreted to extra-cellular space by fusing with secretion signal peptides from alpha-amylase and beta-lactamase. In this study, we have successfully generated synthetic genetic materials to produce four chimeric mycotoxin-detoxifying enzymes. The levels of extracellular secretion is also characterized and analyzed. The project will allow a mass production of detoxification enzymes in cost effective way, preventing the squandering of harvested crops, and limiting mycotoxin-related diseases. Increased access to these proteins will have an immense commercial, industrial, agricultural, and health impact.

Team Members

Gha Young Lee

Junior at Torrey Pines High School

Michael Margolis

Junior at Torrey Pines High School

Brandon Read

Senior at Torrey Pines High School

Mokhshan Ramachandran

Senior at Torrey Pines High School

Brian Choi

Senior at Torrey Pines High School

Anisa Malangone

Junior at Torrey Pines High School

Victoria Ouyang

Junior at Torrey Pines High School

Melinda Wang

Junior at Torrey Pines High School

Christina Baek

Sophomore at Torrey Pines High School

Evan Kallenberg

Senior at Torrey Pines High School

Ellen Ouyang

Sophomore at Canyon Crest Academy

Daniel Sands

Junior at Canyon Crest Academy

Aidan Kahng

Sophomore at Torrey Pines High School

Zilu Pan

Sophomore at Carmel Canyon Academy

Nikki Nikkhoy

Junior at Torrey Pines High School

Alexander Wen

Freshman at Torrey Pines High School

Amanda Matheson

Sophomore at Carmel Canyon Academy

Julia Wisnia

Freshman at Carmel Canyon Academy