Team:TP CC-SanDiego/Members
From 2014hs.igem.org
(Difference between revisions)
Line 439: | Line 439: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2> | + | <h2>Michael Margolis</h2> |
<h3>Junior at Torrey Pines High School</h3> | <h3>Junior at Torrey Pines High School</h3> | ||
<p></p> | <p></p> | ||
Line 446: | Line 446: | ||
</div> | </div> | ||
<div id="Bio2" class="Info"> | <div id="Bio2" class="Info"> | ||
- | <div class="InfoImg"><img src=""></div> | + | <div class="InfoImg"><img src="https://static.igem.org/mediawiki/2013hs/e/e2/GhaYoungPortrait%28s%29.jpg"></div> |
<div class="Text"> | <div class="Text"> | ||
- | <h2> | + | <h2>Gha Young Lee</h2> |
<h3>Junior at Torrey Pines High School</h3> | <h3>Junior at Torrey Pines High School</h3> | ||
<p></p> | <p></p> | ||
Line 475: | Line 475: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Anisa Malangone</h2> |
- | <h3></h3> | + | <h3>Junior at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> | ||
Line 484: | Line 484: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Victoria Ouyang</h2> |
- | <h3></h3> | + | <h3>Junior at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> | ||
Line 493: | Line 493: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Melinda Wang</h2> |
- | <h3></h3> | + | <h3>Junior at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 501: | Line 501: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Christina Baek</h2> |
- | <h3></h3> | + | <h3>Sophomore at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 509: | Line 509: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Evan Kallenberg</h2> |
- | <h3></h3> | + | <h3>Senior at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> | ||
Line 518: | Line 518: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Ellen Ouyang</h2> |
- | <h3></h3> | + | <h3>Sophomore at Canyon Crest Academy</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 526: | Line 526: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Daniel Sands</h2> |
- | <h3></h3> | + | <h3>Junior at Canyon Crest Academy</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 534: | Line 534: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Aidan Kahng</h2> |
- | <h3></h3> | + | <h3>Sophomore at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 542: | Line 542: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Zilu Pan</h2> |
- | <h3></h3> | + | <h3>Sophomore at Carmel Canyon Academy</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> | ||
Line 551: | Line 551: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Nikki Nikkhoy</h2> |
- | <h3></h3> | + | <h3>Junior at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> | ||
Line 560: | Line 560: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Alexander Wen</h2> |
- | <h3></h3> | + | <h3>Freshman at Torrey Pines High School</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 568: | Line 568: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Amanda Matheson</h2> |
- | <h3></h3> | + | <h3>Sophomore at Carmel Canyon Academy</h3> |
<p></p> | <p></p> | ||
</div> | </div> | ||
Line 576: | Line 576: | ||
<div class="InfoImg"><img src=""></div> | <div class="InfoImg"><img src=""></div> | ||
<div class="Text"> | <div class="Text"> | ||
- | <h2></h2> | + | <h2>Julia Wisnia</h2> |
- | <h3></h3> | + | <h3>Freshman at Carmel Canyon Academy</h3> |
<p></p> | <p></p> | ||
<h3></h3> | <h3></h3> |
Revision as of 23:28, 9 March 2014
{
STATISTICS
Statistics that are quite relevant to the nature of this experiment
Statistics that are quite relevant to the nature of this experiment
Toxicity of aflatoxin is 10 times that of hydrocyanic acid and 68 times of arsenic.
This disease is the third-leading cause of cancer death globally according to WHO (2008), with about 550,000–600,000 new cases each year.
This disease is the third-leading cause of cancer death globally according to WHO (2008), with about 550,000–600,000 new cases each year
ENGINEERING
E. Coli Capable of Extracelluar Secretion of Mycotoxin Detoxifying Enzymes
E. Coli Capable of Extracelluar Secretion of Mycotoxin Detoxifying Enzymes
Microfungi that produce harmful mycotoxins flourish on improperly-stored nuts, grains, meat, and dairy. They especially thrive in developing countries, where the lack of advanced food storage and mycotoxin exposure causes 40% of the diseases. To lessen the problem, our team engineered E. coli strains using synthetic biology tools to produce chimeric mycotoxin-degrading fungal enzymes, Aflatoxin-Detoxifizyme (ADTZ) and Zearalenone Hydrolase (ZHD101), which are designed to be secreted to extra-cellular space by fusing with secretion signal peptides from alpha-amylase and beta-lactamase. In this study, we have successfully generated synthetic genetic materials to produce four chimeric mycotoxin-detoxifying enzymes. The levels of extracellular secretion is also characterized and analyzed. The project will allow a mass production of detoxification enzymes in cost effective way, preventing the squandering of harvested crops, and limiting mycotoxin-related diseases. Increased access to these proteins will have an immense commercial, industrial, agricultural, and health impact.