Team:Shenzhen SFLS

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You are provided with this team page template with which to start the iGEM season.  You may choose to personalize it to fit your team but keep the same "look." Or you may choose to take your team wiki to a different level and design your own wiki.  You can find some examples <a href="https://2009.igem.org/Help:Template/Examples">HERE</a>.
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{|align="justify"
 
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|You can write a background of your team here.  Give us a background of your team, the members, etc.  Or tell us more about something of your choosing.
 
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|[[Image:Shenzhen_SFLS_logo.png|200px|right|frame]]
 
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''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
 
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|[[Image:Shenzhen_SFLS_team.png|right|frame|Your team picture]]
 
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|align="center"|[[Team:Shenzhen_SFLS | Team Shenzhen_SFLS]]
 
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{| style="color:#1b2c8a;background-color:#0c6;" cellpadding="3" cellspacing="1" border="1" bordercolor="#fff" width="62%" align="center"
 
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!align="center"|[https://igem.org/Team.cgi?year=2013&division=high_school&team_name=Shenzhen_SFLS Official Team Profile]
 
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===Team===
 
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Tell us about your team, your school!
 
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===Project===
 
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====Project Description====
 
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Shenzhen_SFLS 2014 project description
 
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=====To begin with=====
 
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Aflatoxin B1 generated by ''Aspergillus flavus'' is a kind of lethal toxin that always contaminates the grains we  eat. Aimed to minimize the harm, our project consists of 3 parts from different aspects: killing ''Aspergillus flavus'', neutralizing aflatoxin B1, and reducing the virulence of aflatoxin B1 by turning it into weaker aflatoxin M1.
 
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=====Killing Aspergillus flavus=====
 
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Our engineered bacteria will increase its output of antifungal compounds (which can kill ''Aspergillus flavus'') drastically after being inplanted the engineered circuit. Therefore, this process greatly improves the efficiency of the delimitation of ''Aspergillus flavus''.
 
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=====Neutralizing Aflatoxin B1=====
 
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By optimizing the circuit, aflatoxin will be combined with certain antibodies, and further be immobilized on ''E.coli''’s membrane protein.
 
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=====Transforming toxic aflatoxin B1 into aflatoxin M1=====
 
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It will produce astaxanthin to transform fatal aflatoxin B1 into less toxic aflatoxin M1 after its circuit is constructed. In this way, those toxicated grains  would be detoxified and would even reach edible standard. We are now trying to improve the yield of astaxant.
 
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=====In conclusion=====
 
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As long as the plan is carried out smoothly, three circuits would be connected into a system. The system will start to produce antifungal compounds automatically once aflatoxin B1 is detected. At the same time, it will trigger ''E.coli'' to produce the antibody. Once the antibody is immobilized on the membrane protein, astaxanthin will start to be generated by. As a result, aflatoxin B1 is transformed into aflatoxin M1. 
 
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If our project is carried out successfully and is applied in real life, human beings would benefit from it to a great extent. In fact, aflatoxin contamination in agriculture and animal husbandry causes a loss of hundreds of million dollars per year. Despite the harsh current situation, we still believe that our relentless effort will bring the problem to an end. The contaminated grains would be detoxified until they are eligible. To be optimistic, many problems the whole population face about human health such as the storage of grains, the food's safety and medical hygiene problems would be solved by our project.
 
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===Notebook===
 
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Show us how you spent your days.
 
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===Results/Conclusions===
 
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What did you achieve over the course of your semester?
 
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===Safety===
 
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What safety precautions did your team take? Did you take a safety training course? Were you supervised at all times in the lab?
 
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===Attributions===
 
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Who worked on what?
 
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===Human Practices===
 
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What impact does/will your project have on the public? 
 
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===Fun!===
 
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What was your favorite team snack?? Have a picture of your team mascot?
 
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Latest revision as of 20:10, 7 October 2014

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