Team:CAPS Kansas/Gallery

From 2014hs.igem.org

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<h1> Fun </h1>
<h1> Fun </h1>
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<center><img src="https://static.igem.org/mediawiki/2014hs/6/67/We_Like_Synthetic_Biology.png" width="600"></center><br>
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<br>
<p>Who says that science can't be fun?</p>
<p>Who says that science can't be fun?</p>
<br>
<br>
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<img src="https://static.igem.org/mediawiki/2014hs/0/05/3185999.gif">
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<br>
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<br><br>
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<b>Cyano Machine</b>
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<b>Glycolysis: A Poem</b>
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<br> To the tune of Yellow Submarine
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<br> by Alec Adams <br><br>
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<br> by Muriel Eaton (with help from my friends Lennon and McCartney) <br><br>
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Glycolysis always just starts with glucose, <br>
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In the cytosol, now glucose where do you go? <br>
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It could fly away, to the extracellular space, <br>
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But it gets phosphorylated by hexokinase, <br>
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It costs ATP, to make G-6-P, <br>
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But now it's trapped in the cell, and can proceed, <br>
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If there's plenty of ATP, and insulin, <br>
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Then we've got the conditions to make glycogen, <br>
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Product inhibition by HK's alright, <br>
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But  we need ATP: we isomerize... <br>
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To fructose-6-phosphate, are you listening yet? <br>
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Cause PFK's the rate limiting step, <br>
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Inhibited yes, by allosterically fitting, <br>
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And changing the enzyme, it's finicky, this could be... <br>
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From PCr, ATP and apparently, <br>
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Citrate and H plus also works merrily, <br>
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To enhance, the rate take a stance, <br>
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With ADP, AMP, Pi and dance, <br>
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One last time, ATP is consumed, <br>
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To make fructose-1-6-diphosphate, it's all true, <br>
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That 6 carbon has to go, all the way, <br>
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To 3 carbon backbones, by aldolase, <br>
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Making dihydroxyacetone, phosphate, <br>
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And to the other 3-C backbone it can go, <br>
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And isomerize, <br><br>
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To 3-phosphoglyceraldehyde, <br>
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With Pi, the enzyme, is a dehydrogenase , <br>
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It always makes NADH, and that's all it takes, <br>
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But wait, we added a phosphate to the substrate, <br>
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1-3-diphosphoglycerate, <br><br>
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We find ways with a kinase for ATP making, <br>
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The next enzyme catalyzes substrate phosphorylating, <br>
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are we even with ATP? you can believe it, <br>
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Make 3-phosphoglycerate and kinase does speed it, <br>
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Then we do make 2-phosphoglycerate with a mutase, <br>
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Which will enolize to phosphoenopyruvate, <br>
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Now for the "pay-off" as it's often called, <br>
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We get 2 ATP cause we double it alllllll.... <br>
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Of it with pyruvate kinase we control, <br>
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The reaction it happens cause PEP makes it go, <br>
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But it goes slow with PCr and citrate, <br>
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2 net ATP in the end and that's great! <br><br>
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We've gone a long way, and by coming this far, <br>
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Under Construction.
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We make pyruvate and now here we are, <br>
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Are aerobic or anaerobic? <br>
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We can be both, whichever you pick, <br>
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At steady state or low intensity, <br>
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We predominantly do OP-ETC, <br>
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If we need energy fast we can run, <br>
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To LDH, and fermentation, <br>
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H+ is bad, but lactate is fuel, <br>
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It's used in the liver and muscle tissue, <br>
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It's a reduction reaction because, <br>
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We oxidize NADH and H+,<br>
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To cycle it back, as a cofactor, <br>
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For g-3-p-d, H know why it matters, <br>
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Hope you could follow it, that's all there is, <br>
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To explaining the basics of glycolysis! <br><br>
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Revision as of 00:20, 15 June 2014

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Thanks!

Fun


Who says that science can't be fun?



Cyano Machine
To the tune of Yellow Submarine
by Muriel Eaton (with help from my friends Lennon and McCartney)

Under Construction.

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