Inspired by the olfactory ability of canines to detect diseases, we will pursue a long-term project that revolves around the creation of a minimally invasive and inexpensive detection system for lung cancer, through the identification of exhaled biomarkers. Lung cancer is the leading cause of cancer-related death around the world. Twenty-two volatile organic compounds (VOCs) have been distinctly found in the breath of affected patients, creating a viable “fingerprint” for reliable detection (Horvath et al.). This year we focused on creating biosensors for three VOCs: ethanol, formaldehyde, and xylene. We plan to create genetic circuit systems for aldB induced by ethanol, frmR recognition of formaldehyde, and xylR activated by xylene. Our current device will utilize three reporter proteins (CFP, GFP, RFP) to indicate the concentrations of the three VOCs present in an exhaled sample. This research will eventually go into creating a conclusive test for use in the developing world.

Aliquam libero. Vivamus nisl nibh, iaculis vitae, viverra sit amet, ullamcorper vitae, turpis. Aliquam erat volutpat. Vestibulum dui sem, pulvinar sed, imperdiet nec, iaculis nec, leo. Fusce odio. Etiam arcu dui, faucibus eget, placerat vel, sodales eget, orci. Donec ornare neque ac sem. Mauris aliquet. Aliquam sem leo, vulputate sed, convallis at, ultricies quis, justo. Donec nonummy magna quis risus. Quisque eleifend. Phasellus tempor vehicula justo. Aliquam lacinia metus ut elit. Suspendisse iaculis mauris nec lorem. Donec leo. Vivamus fermentum nibh in augue. Praesent a lacus at urna congue rutrum. Nulla enim eros, porttitor eu, tempus id, varius non, nibh. Duis enim nulla, luctus eu, dapibus lacinia, venenatis id, quam. Vestibulum imperdiet, magna nec eleifend rutrum, nunc lectus vestibulum velit, euismod lacinia quam nisl id lorem. Quisque erat. Donec condimentum, urna non molestie semper, ligula enim ornare nibh, quis laoreet eros quam eget ante. Vestibulum pellentesque, justo mollis pretium suscipit, justo nulla blandit libero, in blandit augue justo quis nisl.

Donec condimentum, urna non molestie semper, ligula enim ornare nibh, quis laoreet eros quam eget ante. Aliquam libero. Vivamus nisl nibh, iaculis vitae, viverra sit amet, ullamcorper vitae, turpis. Aliquam erat volutpat. Vestibulum dui sem, pulvinar sed, imperdiet nec, iaculis nec, leo. Fusce odio. Etiam arcu dui, faucibus eget, placerat vel, sodales eget, orci. Donec ornare neque ac sem. Mauris aliquet. Aliquam sem leo, vulputate sed, convallis at, ultricies quis, justo. Donec nonummy magna quis risus. Quisque eleifend. Phasellus tempor vehicula justo. Aliquam lacinia metus ut elit.