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From 2014hs.igem.org

Contents 1 Project 1.1 To begin with 1.2 Neutralizing Aflatoxin B1 1.3 In conclusion

Project

To begin with

Aflatoxin B1 generated by Aspergillus flavus is a kind of lethal toxin that always contaminates the grains we eat. Aimed to minimize the harm, our project will use antibody to neutralize aflatoxin B1.

Neutralizing Aflatoxin B1

By optimizing the circuit, aflatoxin will be combined with certain antibodies, and further be immobilized on E.coli’s membrane protein.

In conclusion

As long as the plan is carried out smoothly, the circuits would be connected into a system. The system will start to produce ScFv and it will automatically neutralize aflatoxin B1. At the same time, the antibody will be pulled back to the cell membrane ofE.coli.

If our project is carried out successfully and is applied in real life, human beings would benefit from it to a great extent. In fact, aflatoxin contamination in agriculture and animal husbandry causes a loss of hundreds of million dollars per year. Despite the harsh current situation, we still believe that our relentless effort will bring the problem to an end. The contaminated grains would be detoxified until they are eligible. To be optimistic, many problems the whole population face about human health such as the storage of grains, the food's safety and medical hygiene problems would be solved by our project.