Results.html

From 2014hs.igem.org

(Difference between revisions)
(Blanked the page)
 
Line 1: Line 1:
 +
{{Team:TP_CC-SanDiego/ContentFix}}
 +
<html>
 +
<head>
 +
<meta charset="utf-8">
 +
<title>iGEM San Diego</title>
 +
<script src="http://code.jquery.com/jquery-1.11.1.min.js"></script>
 +
<script>
 +
$(function() {
 +
  $('a[href*=#]:not([href=#])').click(function() {
 +
    if (location.pathname.replace(/^\//,'') == this.pathname.replace(/^\//,'') && location.hostname == this.hostname) {
 +
      var target = $(this.hash);
 +
      target = target.length ? target : $('[name=' + this.hash.slice(1) +']');
 +
      if (target.length) {
 +
        $('html,body').animate({
 +
          scrollTop: target.offset().top
 +
        }, 1000);
 +
        return false;
 +
      }
 +
    }
 +
  });
 +
});
 +
</script>
 +
<!--<script>
 +
$(document).ready(function() { 
 +
var stickyNavTop = $('.nav').offset().top; 
 +
 
 +
var stickyNav = function(){ 
 +
var scrollTop = $(window).scrollTop(); 
 +
     
 +
if (scrollTop > stickyNavTop) { 
 +
    $('.nav').addClass('sticky'); 
 +
} else { 
 +
    $('.nav').removeClass('sticky'); 
 +
} 
 +
}; 
 +
 
 +
stickyNav(); 
 +
 
 +
$(window).scroll(function() { 
 +
    stickyNav(); 
 +
}); 
 +
}); 
 +
</script>-->
 +
<style>
 +
#content{
 +
width: 100%;
 +
margin: 0;
 +
padding: 0;
 +
background-color:transparent;
 +
border: none;
 +
}
 +
 +
body{
 +
width: 100%;
 +
margin: 0;
 +
padding: 0;
 +
background-color:none;
 +
border: none;
 +
}
 +
#globalwrapper{
 +
width: 100%;
 +
height: 100%;
 +
background: none;
 +
}
 +
 +
#contentSub, #search-controls, .firstHeading, #footer-box, #catlinks, #p-logo {
 +
    display:none;}
 +
#top-section {
 +
    border: none;
 +
    height: 0px;}
 +
#content {
 +
    border: none;}
 +
/* Removes "teams" from the menubar */
 +
#menubar > ul > li:last-child {
 +
    display: none;}
 +
/* Resizes the menubar to fik the links (default is 400px) */
 +
#menubar {
 +
    width: auto;}
 +
body {
 +
    margin: 10px 0 0 0;
 +
    padding: 0;}
 +
#top-section {
 +
    width: 965px;
 +
    height: 0;
 +
    margin: 0 auto;
 +
    padding: 0;
 +
    border: none;}
 +
#menubar {
 +
    font-size: 65%;
 +
    top: -14px;}
 +
.left-menu:hover {
 +
    background-color: transparent;}
 +
#menubar li a {
 +
    background-color: transparent;}
 +
#menubar:hover {
 +
    color: white;}
 +
#menubar li a {
 +
    color: transparent;}
 +
#menubar:hover li a {
 +
    color: white;}
 +
</style>
 +
<!--<link href="style.css" rel="stylesheet" type="text/css">-->
 +
<link href='http://fonts.googleapis.com/css?family=Lato:300' rel='stylesheet' type='text/css'>
 +
<link href="https://e65ae602ef428322892bf5f667f9d51420f9cd4d.googledrive.com/host/0B21Mp8HDTzNfV3llTVVETkdxSjA/style.css" rel="stylesheet" type="text/css">
 +
</head>
 +
 +
<div id="globalwrapper">
 +
<body>
 +
<div id="navbar-wrapper" class="nav">
 +
    <div id="inside-wrapper">
 +
    <div id="logo-holder">
 +
            Logo Will Go Here
 +
        </div>
 +
        <nav id="navbar">
 +
            <a style= href="https://2014hs.igem.org/Team:TP_CC-SanDiego">Home</a>
 +
            <a href="/Team:TP_CC-SanDiego/Project.html">Project</a>
 +
            <a href="Results.html" style="border-bottom: 1px solid #e8e8e8;">Results</a>
 +
            <a href="TheTeam.html">The Team</a>
 +
            <a href="Journal.html">Journal</a>
 +
                <a href="Outreach.html">Outreach</a>
 +
            <a href="Safety.html">Safety</a>
 +
            <a href="igem.org" style="padding-right: 0;">iGEM</a>
 +
        </nav>
 +
        </div>
 +
</div>
 +
   
 +
 +
<div id="header-holder">
 +
<div id="linkheadertwo"></div>
 +
<div id="header-text">
 +
        Engineering<br />
 +
    <span style="font-family: 'Lato'; font-size: 18px;">E. Coli Capable of Extracelluar Secretion of Mycotoxin Detoxifying Enzymes</span>
 +
    </div>
 +
</div>
 +
 +
<div id="phase-wrapper" style="background:url(https://static.igem.org/mediawiki/2014/9/94/G1.jpg);">
 +
  <div id="third-phase">
 +
    <img src="images/bannerphase4 transparent white text.png" width="1070" height="292"/>
 +
    <div id="third-text"> Microfungi that produce harmful mycotoxins flourish on improperly-stored nuts, grains, meat, and dairy. They especially thrive in developing countries, where the lack of advanced food storage and mycotoxin exposure causes 40% of the diseases. To lessen the problem, our team engineered E. coli strains using synthetic biology tools to produce chimeric mycotoxin-degrading fungal enzymes, Aflatoxin-Detoxifizyme (ADTZ) and Zearalenone Hydrolase (ZHD101), which are designed to be secreted to extra-cellular space by fusing with secretion signal peptides from alpha-amylase and beta-lactamase. In this study, we have successfully generated synthetic genetic materials to produce four chimeric mycotoxin-detoxifying enzymes. The levels of extracellular secretion is also characterized and analyzed. The project will allow a mass production of detoxification enzymes in cost effective way, preventing the squandering of harvested crops, and limiting mycotoxin-related diseases. Increased access to th ese proteins will have an immense commercial, industrial, agricultural, and health impact.</div> 
 +
</div>
 +
</div>
 +
 +
<div id="sponsor-footer-wrapper">
 +
<div id="sponsor-footer">
 +
    SPONSORS
 +
    </div>
 +
</div>
 +
 +
</body>
 +
</div>
 +
</html>

Latest revision as of 03:26, 21 June 2014

iGEM San Diego

Engineering
E. Coli Capable of Extracelluar Secretion of Mycotoxin Detoxifying Enzymes
Microfungi that produce harmful mycotoxins flourish on improperly-stored nuts, grains, meat, and dairy. They especially thrive in developing countries, where the lack of advanced food storage and mycotoxin exposure causes 40% of the diseases. To lessen the problem, our team engineered E. coli strains using synthetic biology tools to produce chimeric mycotoxin-degrading fungal enzymes, Aflatoxin-Detoxifizyme (ADTZ) and Zearalenone Hydrolase (ZHD101), which are designed to be secreted to extra-cellular space by fusing with secretion signal peptides from alpha-amylase and beta-lactamase. In this study, we have successfully generated synthetic genetic materials to produce four chimeric mycotoxin-detoxifying enzymes. The levels of extracellular secretion is also characterized and analyzed. The project will allow a mass production of detoxification enzymes in cost effective way, preventing the squandering of harvested crops, and limiting mycotoxin-related diseases. Increased access to th ese proteins will have an immense commercial, industrial, agricultural, and health impact.

Retrieved from "http://2014hs.igem.org/Results.html"