Team:RAMNOTIREN CALGARY

From 2014hs.igem.org

(Difference between revisions)
 
(136 intermediate revisions not shown)
Line 1: Line 1:
-
{|align="justify"
+
<html>
-
|You can write a background of your team here. Give us a background of your team, the members, etc. Or tell us more about something of your choosing.
+
<head>
-
|[[Image:RAMNOTIREN_CALGARY_logo.png|200px|right|frame]]
+
<link rel='stylesheet' type='text/css' href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Stylesheets/indexcss.css?action=raw&ctype=text/css"/>
-
|-
+
-
|
+
<style>
-
''Tell us more about your project.  Give us background.  Use this as the abstract of your project.  Be descriptive but concise (1-2 paragraphs)''
+
h1{
-
|[[Image:RAMNOTIREN_CALGARY_team.png|right|frame|Your team picture]]
+
font-size: 1em;
-
|-
+
                        display: none;
-
|
+
}
-
|align="center"|[[Team:RAMNOTIREN_CALGARY | Team RAMNOTIREN_CALGARY]]
+
-
|}
+
-
<!--- Team Information Link --->
+
                #firstheading {
 +
                        display: none;
 +
                }
 +
h3{
 +
font-size: 25.5px;
 +
}
-
===Team===
+
p {
-
Tell us about your team, your school!
+
text-indent:50px;
 +
}   
 +
#box1 {
 +
width: 990px;
 +
margin-top: 8px;
 +
background: #E6E6E6; /*threedface*/
 +
float: left;
 +
padding-bottom: 20px;
 +
margin-bottom: 13px;
 +
position: relative;
 +
left: -60px;
 +
                     
 +
}
-
===Project===
+
#box1 h3 {
-
What are you working on this semester?
+
padding: 20px 0px 0px 10px;
 +
font-family: arial, verdana, "lucida sans";
 +
                        text-align: center;
 +
                       
 +
}
 +
#box1 p {
 +
padding: 5px 30px 5px 30px;
 +
font-family: arial, verdana, "lucida sans";
 +
font-size: 15px;
 +
}
-
===Notebook===
+
#content {
-
Show us how you spent your days.
+
z-index: 1;
 +
background-color: transparent;
 +
border: none;
 +
padding-bottom: 0;
 +
margin: 0;
 +
width: 100%;
 +
overflow: hidden;
 +
margin-top: -45px !important;
 +
height:auto !important; /* real browsers */
 +
height:100%; /* IE6: treaded as min-height*/
 +
min-height:100%; /* real browsers */
 +
}
 +
#top-section {
 +
z-index: 2;
 +
height: 15px;
 +
margin: 0px;
 +
margin-left: auto;
 +
margin-right: auto;
 +
margin-bottom: 0 !important;
 +
padding:0;
 +
border: none;
 +
font-size: 10px;
 +
}
-
===Results/Conclusions===
+
#p-logo {
-
What did you achieve over the course of your semester?
+
height:1px;
 +
overflow:hidden;
 +
display: none;
 +
}
 +
#search-controls {
 +
overflow:hidden;
 +
display:block;
 +
background: none;
 +
position: absolute;
 +
top: 100px;
 +
right: 40px;
 +
}
 +
 +
.left-menu {
 +
width: 500px !important;
 +
display:block;
 +
margin-top:-80px;
 +
border: none;
 +
text-align: right;
 +
}
-
===Safety===
+
.left-menu ul {
-
What safety precautions did your team take? Did you take a safety training course? Were you supervised at all times in the lab?
+
border: none;
 +
}
 +
#menubar.right-menu {
 +
width:300px;
 +
display:block;
 +
float:left;
 +
margin-top:-80px;
 +
border: none;
 +
}
-
===Attributions===
+
.right-menu ul {
-
Who worked on what?
+
border: none;
 +
width: 300px;
 +
}
 +
.visualClear {
 +
display: none;
 +
}
-
===Human Practices===
+
.firstHeading {
-
What impact does/will your project have on the public? 
+
display: block;
 +
}
-
===Fun!===
+
#search-controls {
-
What was your favorite team snack?? Have a picture of your team mascot?
+
display:none;
 +
}
 +
#siteSub {
 +
display: none;
 +
}
 +
#contentSub {
 +
display: none;
 +
}
-
<forum_subtle />
+
p:first-child {
 +
display: block;
 +
}
 +
 
 +
h1{
 +
border:none;
 +
width: 100%;
 +
clear: both;
 +
}
 +
 
 +
 
 +
.progress{
 +
display: none;
 +
}
 +
 
 +
#vidbutt{
 +
position: relative;
 +
top:0px;
 +
left:-60px;
 +
background-color: #e6e6e6;
 +
padding: 0px 15px 0px 15px;
 +
border-radius: 5px;
 +
}
 +
 
 +
#notebutt{
 +
position: relative;
 +
top: -300px;
 +
left: 286px;
 +
background-color: #e6e6e6;
 +
padding: 0px 15px 20px 15px;
 +
border-radius: 5px;
 +
}
 +
 
 +
 
 +
 
 +
        #tweets{
 +
      position: relative;
 +
top:-834px;
 +
left:642px;
 +
      width: 280px;   
 +
}
 +
      #countdown{
 +
      position: relative;
 +
top: -815px;
 +
left:642px;
 +
}
 +
 
 +
 
 +
 
 +
    #sponsorsbox{
 +
clear: both;
 +
position: relative;
 +
                top: -600px;
 +
                left: -70px;
 +
width: 1005px;
 +
margin: 4px 0px;
 +
background: #EEEEEE;
 +
                border-radius: 3px;
 +
}
 +
#sponsorsbox h4{
 +
padding: 20px 20px 0px 20px
 +
}
 +
#sponsorsbox p{
 +
padding: 0px 20px;
 +
}
 +
#sponsorsbox table{
 +
width: 950px;
 +
margin-left: auto;
 +
margin-right: auto;
 +
background: #EEEEEE;
 +
}
 +
#sponsorsbox td{
 +
padding: 15px 0px;
 +
width: 300px;
 +
}
 +
#sponsorsbox img{
 +
display: block;
 +
margin-right: auto;
 +
margin-left: auto;
 +
}
 +
 
 +
    #exp1{
 +
      position: relative;
 +
top:-310px;
 +
left:-58px;
 +
      background-color: #e6e6e6;
 +
      padding: 10px 10px 10px 10px;
 +
width: 308px;
 +
    }
 +
 
 +
    #exp2{
 +
      position: relative;
 +
top:-405px;
 +
left: 288px;
 +
      background-color: #e6e6e6;
 +
            padding: 10px 10px 10px 10px;
 +
width: 308px;
 +
    }
 +
</style>
 +
 
 +
<script type="text/javascript" src ="https://2014hs.igem.org/common/jquery-latest.min.js"></script>
 +
 
 +
<script type="text/javascript">
 +
    function slider() {
 +
        var $current = $('#slides IMG.current');
 +
 
 +
        if ( $current.length == 0 ) $current = $('#slides IMG:last');
 +
        var $next =  $current.next().length ? $current.next()
 +
            : $('#slides IMG:first');
 +
 
 +
          $current.addClass('previous');
 +
        $next.css({opacity: 0.0})
 +
            .addClass('current')
 +
            .animate({opacity: 1.0}, 2500, function() {
 +
                $current.removeClass('current previous');
 +
    });
 +
 
 +
    var $navicurrent = $('.progress li.current');
 +
    if($navicurrent.length ==0) $navicurrent = $('.progress li:last');
 +
    var $navinext = $navicurrent.next().length ? $navicurrent.next() : $('.progress li:first');
 +
    $navicurrent.addClass('previous');
 +
    $navicurrent.removeClass('current previous');
 +
    $navinext.addClass('current').animate({opacity: 1.0}, 2500, function() {
 +
            });
 +
 
 +
    $('.progress li').click(function(){
 +
       
 +
        var $ncurrent = $(this);
 +
            $('.progress li').removeClass('current').removeClass('previous');
 +
            $('#slides IMG').removeClass('current').removeClass('previous');
 +
            $ncurrent.addClass('current');
 +
            var ncurrentindex = $ncurrent.index();
 +
        if(  ncurrentindex=== 0) $current = $('#slides IMG:first');
 +
            if(  ncurrentindex=== 1) $current = $('#slides IMG:eq(1)');
 +
            if(  ncurrentindex=== 2) $current = $('#slides IMG:eq(2)');
 +
            if(  ncurrentindex=== 3) $current = $('#slides IMG:last');
 +
            $current.addClass('current');
 +
 
 +
    });
 +
 
 +
    }
 +
 
 +
    $(function() {
 +
        setInterval( "slider()", 5000 );
 +
    });
 +
 
 +
    /*js for twitter feed*/
 +
    !function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");
 +
 +
</script>
 +
 
 +
<script type="text/javascript" src="https://ajax.googleapis.com/ajax/libs/jquery/1.7.2/jquery.js"></script>
 +
 
 +
</head>
 +
<body>
 +
<div id="globalWrapper"/>
 +
 
 +
    <div id="main-content"/>
 +
 
 +
    <div id="topmenubar" class="topleft-menu"/>
 +
    <ul>
 +
    <li><a href="https://igem.org/Team_List?year=2014&division=high_school" style='color:#014457; cursor:pointer' target="blank">teams</a></li>
 +
    <li class='selected'><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY">Page</a></li>
 +
<li class='new'><a href="https://2014hs.igem.org/wiki/index.php?title=Talk:Team:RAMNOTIREN_CALGARY&action=edit&redlink=1">Discussion</a></li>
 +
    <li><a href="https://2014hs.igem.org/wiki/index.php?title=Team:RAMNOTIREN_CALGARY&action=edit">View Source</a></li>
 +
    <li><a href="https://2014hs.igem.org/wiki/index.php?title=Team:RAMNOTIREN_CALGARY&action=history">History</a></li>
 +
    <li><a href="https://igem.org/Login">Log in</a></li>
 +
</ul>
 +
</div>
 +
 
 +
<header>
 +
<div id="slides">
 +
    <img  src="https://static.igem.org/mediawiki/2014hs/9/96/Banner1.jpg" width="968" height="272" alt="" class="current" />
 +
    <img  src="https://static.igem.org/mediawiki/2014hs/0/00/Dnabg.jpg" width="968" height="272" alt="" />
 +
    <img  src="https://static.igem.org/mediawiki/2014hs/9/96/Banner1.jpg" width="968" height="272" alt="" />
 +
    <img  src="https://static.igem.org/mediawiki/2014hs/0/00/Dnabg.jpg" width="968" height="272" alt="" />
 +
</div>
 +
<ul class="progress">
 +
    <li class="current"><a href="#n_0">1</a> </li>
 +
    <li><a href="#n_1">2</a> </li>
 +
    <li><a href="#n_2">3</a> </li>
 +
    <li><a href="#n_3">4</a> </li>
 +
</ul>
 +
 
 +
<div>
 +
<ul id="menu">
 +
 
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY‎" id="homelink">Home</a></li>
 +
 
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Members" id="teamlink">Team</a>
 +
<ul>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Members">Members</a></li>
 +
<li><a href="https://igem.org/Team.cgi?id=1295" target="_blank">Official Profile</a></li>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/AboutCMHS">About CMHS</a></li>
 +
</ul>
 +
</li>
 +
 
 +
                                  <li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Project/Content" id="projectlink">Content</a>
 +
<ul>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Project/Content">Overview</a></li>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/HumanPractices">Human Practices</a></li>
 +
                                                <li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Project/Safety">Safety</a></li>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/References">References</a></li>
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Attributions">Attributions</a></li>
 +
</ul>
 +
</li>
 +
 
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Parts" id="partslink">Parts</a></li>
 +
 
 +
<li><a class="drop" href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Notebook" id="notebooklink">Notebook</a></li>
 +
 
 +
<li><a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Protocols" id="protocollink">Protocols</a></li>
 +
 
 +
<li><a href="https://2014hs.igem.org" target="_blank">iGEM</a></li>
 +
</ul>
 +
</div>
 +
</header>
 +
 
 +
<div id="box1"> <!--align="justify"-->
 +
<h3>Choking Cancer</h3>
 +
<p>Every year approximately eight million people die of cancer, and an additional fourteen million are diagnosed with the disease. The World Heath Organization predicts that without immediate action these numbers will increase by eighty percent by the year 2030.</p><p>Cancer needs an abundant source of oxygenated blood to grow. To achieve this cancer cells release angiogenic factors that promote vascular growth. Without these factors, cancer is unable to survive.  Consequently, current treatments focus on targeting/inhibiting the angiogenic factors released by cancer cells. Targeted therapy has also been a successful treatment option.</p><p>Our project aims to combine these two therapeutic approaches to create a synthetic biological machine that seeks out cancer cells and inhibits angiogenesis. We plan to design a bacterium that in the presence of cancer cells secretes an anti-angiogenic factor.  This will inhibit the growth of the capillary system that is crucial for cancer cell survival.</p>
 +
 
 +
</div>
 +
 
 +
<div id="button1">
 +
  <a href="http://www.youtube.com/watch?v=C_5Z31mUmtc"><img id="vidbutt" src="https://static.igem.org/mediawiki/2014hs/6/67/VideoButton.png" width="300px" height="300px"></a>
 +
</div>
 +
 
 +
<div id="button2">
 +
  <a href="https://2014hs.igem.org/Team:RAMNOTIREN_CALGARY/Notebook"><img id="notebutt" src="https://static.igem.org/mediawiki/2014hs/9/95/Notebook.png" width="300px" height="300px"></a>
 +
 
 +
<div id="exp1">
 +
<p>Click here to see the introductory video we used to familiarize ouselves with what we would be researching. </p>
 +
</div>
 +
 
 +
<div id="exp2">
 +
<p>Here is a record of our. We also want to thank everybody who helped us along the way!</p>
 +
</div>
 +
 
 +
 
 +
  <div id="tweets">
 +
    <a class="twitter-timeline"  href="https://twitter.com/CentraliGEM"  data-widget-id="475046068170674176">Tweets by @CentraliGEM</a>
 +
    <script>!function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],p=/^http:/.test(d.location)?'http':'https';if(!d.getElementById(id)){js=d.createElement(s);js.id=id;js.src=p+"://platform.twitter.com/widgets.js";fjs.parentNode.insertBefore(js,fjs);}}(document,"script","twitter-wjs");</script>
 +
</div>
 +
 
 +
<div id="countdown">
 +
<iframe src="http://free.timeanddate.com/countdown/i478w11x/n43/cf111/cm0/cu4/ct3/cs1/ca2/co1/cr2/ss0/cac000/cpc000/pc9542aa/tc9542aa/fs90/szw256/szh108/tatCountdown%20to%20iGEM%20Jamboree/tac000/tptTime%20since%20Event%20started%20in/tpc000/iso2014-06-26T00:00:00/bo2" frameborder="0" width="258" height="110"></iframe>
 +
 
 +
</div>
 +
 
 +
 
 +
<div id="sponsorsbox">
 +
  <h4>
 +
    Our Sponsors
 +
  </h4>
 +
  <table>
 +
    <tr>
 +
      <td><a href="http://www.albertatechfutures.ca" target="_blank"><img style="width: 284px;" src="https://static.igem.org/mediawiki/2014hs/7/7a/AlbertaInno.png"/></a></td>
 +
      <td><a href="http://www.albertatechfutures.ca/AcademicProgramsiCORE/geekStarter.aspx" target="_blank"><img style="width: 284px;" src="https://static.igem.org/mediawiki/2014hs/0/0d/GeekStarter.png"/></a></td>
 +
      <td><a href="http://schools.cbe.ab.ca/b823/default.html" target="_blank"><img style="width= 284px;" src="https://static.igem.org/mediawiki/2014hs/6/6a/Ram.png"/></a></td>
 +
    </tr>
 +
  </table>
 +
</div>
 +
 
 +
</body>
 +
</html>

Latest revision as of 04:02, 21 June 2014

Choking Cancer

Every year approximately eight million people die of cancer, and an additional fourteen million are diagnosed with the disease. The World Heath Organization predicts that without immediate action these numbers will increase by eighty percent by the year 2030.

Cancer needs an abundant source of oxygenated blood to grow. To achieve this cancer cells release angiogenic factors that promote vascular growth. Without these factors, cancer is unable to survive. Consequently, current treatments focus on targeting/inhibiting the angiogenic factors released by cancer cells. Targeted therapy has also been a successful treatment option.

Our project aims to combine these two therapeutic approaches to create a synthetic biological machine that seeks out cancer cells and inhibits angiogenesis. We plan to design a bacterium that in the presence of cancer cells secretes an anti-angiogenic factor. This will inhibit the growth of the capillary system that is crucial for cancer cell survival.

Click here to see the introductory video we used to familiarize ouselves with what we would be researching.

Here is a record of our. We also want to thank everybody who helped us along the way!

Our Sponsors

Retrieved from "http://2014hs.igem.org/Team:RAMNOTIREN_CALGARY"